TOE1 Antibody

Code CSB-PA024041GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
TOE1
Alternative Names
Target of EGR1 protein 1 antibody; target of EGR1; member 1 antibody; Toe1 antibody; TOE1_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human TOE1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC,IF
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Inhibits cell growth rate and cell cycle. Induces CDKN1A expression as well as TGF-beta expression. Mediates the inhibitory growth effect of EGR1. Involved in the maturation of snRNAs and snRNA 3'-tail processing.
Gene References into Functions
  1. Human cells with reduced levels of TOE1 accumulated 3'-end-extended pre-snRNA. PMID: 28092684
  2. Antiviral potency of TOE1 and its cell-penetrating capability have been identified to lie within a 35-amino-acid region containing the nuclear localization sequence PMID: 26056259
  3. TOE1 has a role in the growth inhibitory activity of Egr1 PMID: 12562764
Involvement in disease
Pontocerebellar hypoplasia 7 (PCH7)
Subcellular Location
Nucleus, nucleolus. Nucleus speckle. Note=Localizes to nuclear speckles.
Protein Families
CAF1 family
Tissue Specificity
Widely expressed.
Database Links

HGNC: 15954

OMIM: 613931

KEGG: hsa:114034

STRING: 9606.ENSP00000361162

UniGene: Hs.525091

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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