TP53INP2 Antibody

Code CSB-PA117430
Size US$297
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  • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using TP53INP2 antibody.
  • Immunofluorescence analysis of MCF-7 cells, using TP53INP2 antibody.
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Product Details

Full Product Name
Rabbit anti-Mus musculus (Mouse) Tp53inp2 Polyclonal antibody
Uniprot No.
Target Names
Tp53inp2
Alternative Names
Tp53inp2 antibody; Dor antibody; Trp53inp2 antibody; Tumor protein p53-inducible nuclear protein 2 antibody; Diabetes and obesity-regulated protein antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthesized peptide derived from internal of Human TP53INP2.
Immunogen Species
Mus musculus (Mouse)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,IHC,IF
Recommended Dilution
Application Recommended Dilution
IHC 1:50-1:100
IF 1:100-1:500
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA.
Gene References into Functions
  1. TP53INP2 repression is part of an adaptive mechanism aimed at preserving muscle mass under conditions in which insulin action is deficient. PMID: 24713655
Subcellular Location
Cytoplasm, cytosol. Nucleus. Nucleus, PML body. Cytoplasmic vesicle, autophagosome.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 322 (CUBIO Innovation Center), Houston, TX 77054, USA
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