Name: TRABD2B Antibody, HRP conjugated
Brand: CUSABIO
SKU: CSB-PA406235LB01HU

Product Details

Full Product Name	Rabbit anti-Homo sapiens (Human) TRABD2B Polyclonal antibody
Uniprot No.	A6NFA1
Target Names	TRABD2B
Alternative Names	TRABD2B antibody; HKAT antibody; TIKI2 antibody; Metalloprotease TIKI2 antibody; EC 3.4.-.- antibody; Heart antibody; kidney and adipose-enriched transmembrane protein homolog antibody; TRAB domain-containing protein 2B antibody
Raised in	Rabbit
Species Reactivity	Human
Immunogen	Recombinant Human Metalloprotease TIKI2 protein (195-405AA)
Immunogen Species	Homo sapiens (Human)
Conjugate	HRP
Clonality	Polyclonal
Isotype	IgG
Purification Method	Antigen Affinity Purified
Concentration	It differs from different batches. Please contact us to confirm it.
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form	Liquid
Tested Applications	ELISA
Protocols	ELISA Protocol
Troubleshooting and FAQs	Antibody FAQs
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time	Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Target Background

Function	Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation.
Gene References into Functions	Results of the present study indicate that TIKI2 is upregulated in renal cell carcinoma tissues and plays an oncogenic role in renal cell carcinoma PMID: 26942462 examination of the structural prediction and identification of the active site residues of human TIKI2 PMID: 26631728 provided evidence that reduced expression of TIKI family protein in osteosarcoma may participate in the progression of osteosarcoma and restoring its expression was able to impair the growth of osteosarcoma PMID: 24771064 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
Subcellular Location	Cell membrane; Single-pass type I membrane protein.
Protein Families	TIKI family
Database Links	HGNC: 44200 OMIM: 614913 KEGG: hsa:388630 STRING: 9606.ENSP00000456730 UniGene: Hs.61504

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TRABD2B Antibody, HRP conjugated

Code	CSB-PA406235LB01HU
Size	US$299
Have Questions?	Leave a Message or Start an on-line Chat