TRAM2 Antibody

Code CSB-PA624011LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA624011LA01HU at dilution of 1:100

  • Immunofluorescent analysis of MCF-7 cells using CSB-PA624011LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TRAM2 Polyclonal antibody
Uniprot No.
Target Names
TRAM2
Alternative Names
TRAM2; KIAA0057; Translocating chain-associated membrane protein 2
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Translocating chain-associated membrane protein 2 protein (316-370AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The TRAM2 Antibody (Product code: CSB-PA624011LA01HU) is Non-conjugated. For TRAM2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA624011LB01HU TRAM2 Antibody, HRP conjugated ELISA
FITC CSB-PA624011LC01HU TRAM2 Antibody, FITC conjugated
Biotin CSB-PA624011LD01HU TRAM2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) concentration may be necessary for the function of molecular chaperones involved in collagen folding. Required for proper insertion of the first transmembrane helix N-terminus of TM4SF20 into the ER lumen, may act as a ceramide sensor for regulated alternative translocation (RAT).
Gene References into Functions
  1. TRAM2, as a part of the translocon, is required for the biosynthesis of type I collagen by coupling the activity of SERCA2b with the activity of the translocon PMID: 14749390
Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
TRAM family
Database Links

HGNC: 16855

OMIM: 608485

KEGG: hsa:9697

STRING: 9606.ENSP00000182527

UniGene: Hs.520182

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