TRAPPC11 Antibody, FITC conjugated

Code CSB-PA801799LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TRAPPC11 Polyclonal antibody
Uniprot No.
Target Names
TRAPPC11
Alternative Names
TRAPPC11 antibody; C4orf41 antibody; Trafficking protein particle complex subunit 11 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Trafficking protein particle complex subunit 11 protein (704-836AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage.
Gene References into Functions
  1. Recessive mutations in TRAPPC11 and GOSR2 are associated with congenital muscular dystrophy and hypoglycosylation of alpha-dystroglycan. PMID: 29855340
  2. The identified novel TRAPPC11 mutation represents an expansion of the myopathy phenotype described before and is characterised particularly by achalasia, alacrima, neurological and muscular phenotypes. PMID: 27707803
  3. TRAPPC11 role in protein glycosylation and lipid-linked oligosaccharides biosynthesis PMID: 26912795
  4. Homozygous mutations in the membrane trafficking component TRAPPC11 causes a form of autosomal-recessive, slowly progressive limb girdle muscular dystrophy with childhood onset and high serum creatine kinase. PMID: 23830518
Involvement in disease
Limb-girdle muscular dystrophy 2S (LGMD2S)
Subcellular Location
Golgi apparatus. Golgi apparatus, cis-Golgi network.
Protein Families
TRAPPC11 family
Database Links

HGNC: 25751

OMIM: 614138

KEGG: hsa:60684

STRING: 9606.ENSP00000335371

UniGene: Hs.443240

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