TRAPPC11 Antibody, HRP conjugated

Code CSB-PA801799LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TRAPPC11 Polyclonal antibody
Uniprot No.
Target Names
TRAPPC11
Alternative Names
TRAPPC11 antibody; C4orf41 antibody; Trafficking protein particle complex subunit 11 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Trafficking protein particle complex subunit 11 protein (704-836AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage.
Gene References into Functions
  1. Recessive mutations in TRAPPC11 and GOSR2 are associated with congenital muscular dystrophy and hypoglycosylation of alpha-dystroglycan. PMID: 29855340
  2. The identified novel TRAPPC11 mutation represents an expansion of the myopathy phenotype described before and is characterised particularly by achalasia, alacrima, neurological and muscular phenotypes. PMID: 27707803
  3. TRAPPC11 role in protein glycosylation and lipid-linked oligosaccharides biosynthesis PMID: 26912795
  4. Homozygous mutations in the membrane trafficking component TRAPPC11 causes a form of autosomal-recessive, slowly progressive limb girdle muscular dystrophy with childhood onset and high serum creatine kinase. PMID: 23830518
Involvement in disease
Limb-girdle muscular dystrophy 2S (LGMD2S)
Subcellular Location
Golgi apparatus. Golgi apparatus, cis-Golgi network.
Protein Families
TRAPPC11 family
Database Links

HGNC: 25751

OMIM: 614138

KEGG: hsa:60684

STRING: 9606.ENSP00000335371

UniGene: Hs.443240

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