TRIM26 Antibody

Datasheet

Code	CSB-PA619638LA01HU
Size	US$166
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Image	IHC image of CSB-PA619638LA01HU diluted at 1:300 and staining in paraffin-embedded human endometrial cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) TRIM26 Polyclonal antibody

Uniprot No.

Q12899

Target Names

TRIM26

Alternative Names

Acid finger protein antibody; AFP antibody; CAM25547 antibody; RING finger protein 95 antibody; RNF95 antibody; TRI26_HUMAN antibody; TRIM26 antibody; tripartite motif containing 26 antibody; Tripartite motif-containing protein 26 antibody; widely expressed acid zinc finger protein antibody; Zinc finger protein 173 antibody; Zinc finger protein 173; formerly antibody; ZNF173 antibody; ZNF173; formerly antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Tripartite motif-containing protein 26 protein (151-270AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The TRIM26 Antibody (Product code: CSB-PA619638LA01HU) is Non-conjugated. For TRIM26 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA619638LB01HU	TRIM26 Antibody, HRP conjugated	ELISA
FITC	CSB-PA619638LC01HU	TRIM26 Antibody, FITC conjugated
Biotin	CSB-PA619638LD01HU	TRIM26 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:200-1:500

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

E3 ubiquitin-protein ligase which regulates the IFN-beta production and antiviral response downstream of various DNA-encoded pattern-recognition receptors (PRRs). Promotes nuclear IRF3 ubiquitination and proteasomal degradation. Bridges together TBK1 and NEMO during the innate response to viral infection leading to the activation of TBK1.

Gene References into Functions

Autoubiquitination of TRIM26 links TBK1 to NEMO in RLR-mediated innate antiviral immune response PMID: 26611359
Down-regulation of TRIM26 is associated with worse prognosis of hepatocellular carcinoma. PMID: 26043685
In addition to confirming one of the top findings in the meta-analysis, TRIM26, RNF5 and HLA-DRB3 have been identified as potential candidate genes for schizophrenia. PMID: 22433715
The study reports no associations between polymorphisms in TRIM26 and the risk of aspirin-exacerbated respiratory disease in both logistic and regression analyses. PMID: 22294275

Subcellular Location

Cytoplasm. Nucleus.

Protein Families

TRIM/RBCC family

Database Links

HGNC: 12962

OMIM: 600830

KEGG: hsa:7726

STRING: 9606.ENSP00000391879

UniGene: Hs.485041

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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