TRIM26 Antibody, HRP conjugated

Code CSB-PA619638LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TRIM26 Polyclonal antibody
Uniprot No.
Target Names
TRIM26
Alternative Names
Acid finger protein antibody; AFP antibody; CAM25547 antibody; RING finger protein 95 antibody; RNF95 antibody; TRI26_HUMAN antibody; TRIM26 antibody; tripartite motif containing 26 antibody; Tripartite motif-containing protein 26 antibody; widely expressed acid zinc finger protein antibody; Zinc finger protein 173 antibody; Zinc finger protein 173; formerly antibody; ZNF173 antibody; ZNF173; formerly antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Tripartite motif-containing protein 26 protein (151-270AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
E3 ubiquitin-protein ligase which regulates the IFN-beta production and antiviral response downstream of various DNA-encoded pattern-recognition receptors (PRRs). Promotes nuclear IRF3 ubiquitination and proteasomal degradation. Bridges together TBK1 and NEMO during the innate response to viral infection leading to the activation of TBK1.
Gene References into Functions
  1. Autoubiquitination of TRIM26 links TBK1 to NEMO in RLR-mediated innate antiviral immune response PMID: 26611359
  2. Down-regulation of TRIM26 is associated with worse prognosis of hepatocellular carcinoma. PMID: 26043685
  3. In addition to confirming one of the top findings in the meta-analysis, TRIM26, RNF5 and HLA-DRB3 have been identified as potential candidate genes for schizophrenia. PMID: 22433715
  4. The study reports no associations between polymorphisms in TRIM26 and the risk of aspirin-exacerbated respiratory disease in both logistic and regression analyses. PMID: 22294275
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
TRIM/RBCC family
Database Links

HGNC: 12962

OMIM: 600830

KEGG: hsa:7726

STRING: 9606.ENSP00000391879

UniGene: Hs.485041

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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