TRIM45 Antibody

Code CSB-PA572337
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA572337(TRIM45 Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA572337(TRIM45 Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
TRIM45
Alternative Names
FLJ13181 antibody; RING finger protein 99 antibody; RNF99 antibody; TRI45_HUMAN antibody; TRIM45 antibody; Tripartite motif containing 45 antibody; Tripartite motif containing protein 45 antibody; Tripartite motif-containing protein 45 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthetic peptide of Human TRIM45
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
IHC 1:25-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May act as a transcriptional repressor in mitogen-activated protein kinase signaling pathway.
Gene References into Functions
  1. These findings suggest that TRIM45 is a novel tumor suppressor that stabilizes and activates p53 in glioma. PMID: 28542145
  2. The TRIM-FLMN protein TRIM45 directly interacts with RACK1 and negatively regulates PKC-mediated signaling pathway. PMID: 24681954
  3. These findings suggest that TRIM45 acts as a repressor for the NF-kappaB signal and regulates cell growth. PMID: 22634006
  4. TRIM45 may act as a new transcriptional repressor in mitogen-activated protein kinase signaling pathway PMID: 15351693
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
TRIM/RBCC family
Tissue Specificity
Expressed in skeletal muscle, brain, heart and pancreas.
Database Links

HGNC: 19018

OMIM: 609318

KEGG: hsa:80263

STRING: 9606.ENSP00000256649

UniGene: Hs.301526

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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