TRIM45 Antibody

Datasheet

Code	CSB-PA862044LA01HU
Size	US$166
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Image	IHC image of CSB-PA862044LA01HU diluted at 1:200 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) TRIM45 Polyclonal antibody

Uniprot No.

Q9H8W5

Target Names

TRIM45

Alternative Names

FLJ13181 antibody; RING finger protein 99 antibody; RNF99 antibody; TRI45_HUMAN antibody; TRIM45 antibody; Tripartite motif containing 45 antibody; Tripartite motif containing protein 45 antibody; Tripartite motif-containing protein 45 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Tripartite motif-containing protein 45 protein (428-573AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The TRIM45 Antibody (Product code: CSB-PA862044LA01HU) is Non-conjugated. For TRIM45 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA862044LB01HU	TRIM45 Antibody, HRP conjugated	ELISA
FITC	CSB-PA862044LC01HU	TRIM45 Antibody, FITC conjugated
Biotin	CSB-PA862044LD01HU	TRIM45 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:200-1:500

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

May act as a transcriptional repressor in mitogen-activated protein kinase signaling pathway.

Gene References into Functions

These findings suggest that TRIM45 is a novel tumor suppressor that stabilizes and activates p53 in glioma. PMID: 28542145
The TRIM-FLMN protein TRIM45 directly interacts with RACK1 and negatively regulates PKC-mediated signaling pathway. PMID: 24681954
These findings suggest that TRIM45 acts as a repressor for the NF-kappaB signal and regulates cell growth. PMID: 22634006
TRIM45 may act as a new transcriptional repressor in mitogen-activated protein kinase signaling pathway PMID: 15351693

Subcellular Location

Cytoplasm. Nucleus.

Protein Families

TRIM/RBCC family

Tissue Specificity

Expressed in skeletal muscle, brain, heart and pancreas.

Database Links

HGNC: 19018

OMIM: 609318

KEGG: hsa:80263

STRING: 9606.ENSP00000256649

UniGene: Hs.301526

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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