TRIM45 Antibody

Code CSB-PA862044LA01HU
Size US$166
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Image
  • IHC image of CSB-PA862044LA01HU diluted at 1:200 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TRIM45 Polyclonal antibody
Uniprot No.
Target Names
TRIM45
Alternative Names
FLJ13181 antibody; RING finger protein 99 antibody; RNF99 antibody; TRI45_HUMAN antibody; TRIM45 antibody; Tripartite motif containing 45 antibody; Tripartite motif containing protein 45 antibody; Tripartite motif-containing protein 45 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Tripartite motif-containing protein 45 protein (428-573AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The TRIM45 Antibody (Product code: CSB-PA862044LA01HU) is Non-conjugated. For TRIM45 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA862044LB01HU TRIM45 Antibody, HRP conjugated ELISA
FITC CSB-PA862044LC01HU TRIM45 Antibody, FITC conjugated
Biotin CSB-PA862044LD01HU TRIM45 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:200-1:500
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May act as a transcriptional repressor in mitogen-activated protein kinase signaling pathway.
Gene References into Functions
  1. These findings suggest that TRIM45 is a novel tumor suppressor that stabilizes and activates p53 in glioma. PMID: 28542145
  2. The TRIM-FLMN protein TRIM45 directly interacts with RACK1 and negatively regulates PKC-mediated signaling pathway. PMID: 24681954
  3. These findings suggest that TRIM45 acts as a repressor for the NF-kappaB signal and regulates cell growth. PMID: 22634006
  4. TRIM45 may act as a new transcriptional repressor in mitogen-activated protein kinase signaling pathway PMID: 15351693
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
TRIM/RBCC family
Tissue Specificity
Expressed in skeletal muscle, brain, heart and pancreas.
Database Links

HGNC: 19018

OMIM: 609318

KEGG: hsa:80263

STRING: 9606.ENSP00000256649

UniGene: Hs.301526

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