TRIM68 Antibody

Code CSB-PA004718
Size US$100
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  • Western Blot analysis of Jurkat K562 cells using SS-56 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
TRIM68
Alternative Names
TRIM68 antibody; GC109 antibody; RNF137 antibody; SS56 antibody; E3 ubiquitin-protein ligase TRIM68 antibody; EC 2.3.2.27 antibody; RING finger protein 137 antibody; RING-type E3 ubiquitin transferase TRIM68 antibody; SSA protein SS-56 antibody; SS-56 antibody; Tripartite motif-containing protein 68 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of Human SS-56.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:40000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Functions as a ubiquitin E3 ligase. Acts as a coactivator of androgen receptor (AR) depending on its ubiquitin ligase activity.
Gene References into Functions
  1. TRIM68 targets TFG, a novel regulator of IFN production, and in doing so turns off and limits type I IFN production in response to anti-viral detection systems PMID: 24999993
  2. TRIM68 functions as a cofactor for AR-mediated transcription and is likely to be a novel diagnostic tool and a potentially therapeutic target for prostate cancer. PMID: 18451177
Subcellular Location
Cytoplasm, perinuclear region. Nucleus. Note=Colocalized with AR in nucleus.
Protein Families
TRIM/RBCC family
Tissue Specificity
Widely expressed. Expressed at high levels in prostate cancer cell lines. Up-regulation could be restricted to androgen-dependent cells.
Database Links

HGNC: 21161

OMIM: 613184

KEGG: hsa:55128

STRING: 9606.ENSP00000300747

UniGene: Hs.523438

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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