TTC5 Antibody

Datasheet

Code	CSB-PA822676LA01HU
Size	US$166
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Image	Western blot All lanes: TTC5 antibody at 6µg/ml Lane 1: HepG2 whole cell lysate Lane 2: A549 whole cell lysate Lane 3: MCF-7 whole cell lysate Lane 4: Mouse kidney tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 49 kDa Observed band size: 49 kDa
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Product Details
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Target Background

Product Details

Uniprot No.

Q8N0Z6

Alternative Names

TTC5Tetratricopeptide repeat protein 5 antibody; TPR repeat protein 5 antibody; Stress-responsive activator of p300 antibody; Strap antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Tetratricopeptide repeat protein 5 protein (201-440AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The TTC5 Antibody (Product code: CSB-PA822676LA01HU) is Non-conjugated. For TTC5 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA822676LB01HU	TTC5 Antibody, HRP conjugated	ELISA
FITC	CSB-PA822676LC01HU	TTC5 Antibody, FITC conjugated
Biotin	CSB-PA822676LD01HU	TTC5 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2.

Gene References into Functions

Human TTC5, a novel tetratricopeptide repeat domain containing gene, activates p53 and inhibits AP-1 pathway. PMID: 24091941
TTC5 and EP300 cooperate to prevent excessive accumulation of MYC in AML cells and their sensitization to cell death. PMID: 23559008
TTC5 is a novel cofactor regulating GR function in a stress-dependent manner. PMID: 21147850

Subcellular Location

Nucleus. Cytoplasm.

Database Links

HGNC: 19274

KEGG: hsa:91875

STRING: 9606.ENSP00000258821

UniGene: Hs.98553

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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