TTI2 Antibody, FITC conjugated

Datasheet
Code CSB-PA764687LC01HU
Size US$299
Uniprot No. Q6NXR4
Immunogen Recombinant Human TELO2-interacting protein 2 protein (159-264AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs.
Form Liquid
Conjugate FITC
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias TELO2-interacting protein 2, TTI2, C8orf41
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Research Area Cell Biology
Target Names TTI2
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs.
Involvement in disease Mental retardation, autosomal recessive 39 (MRT39)
Protein Families TTI2 family
Database Links

HGNC: 26262

OMIM: 614426

KEGG: hsa:80185

STRING: 9606.ENSP00000353971

UniGene: Hs.742048

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