TTI2 Antibody, FITC conjugated

Datasheet

Code	CSB-PA764687LC01HU
Size	US$166
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) TTI2 Polyclonal antibody

Uniprot No.

Q6NXR4

Target Names

TTI2

Alternative Names

C8orf41 antibody; CH041_HUMAN antibody; TELO2 interacting protein 2provided antibody; TTI2 antibody; Uncharacterized protein C8orf41 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human TELO2-interacting protein 2 protein (159-264AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

FITC

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs.

Gene References into Functions

The findings emphasises the role of the TTI2 gene in the etiology of intellectual disability. PMID: 23956177
TTI1 and TTI2 protect cells from spontaneous DNA damage, and are required for the establishment of the intra-S and G2/M checkpoint. PMID: 20810650

Involvement in disease

Mental retardation, autosomal recessive 39 (MRT39)

Protein Families

TTI2 family

Database Links

HGNC: 26262

OMIM: 614426

KEGG: hsa:80185

STRING: 9606.ENSP00000353971

UniGene: Hs.742048

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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