TUBA8 Antibody

Code CSB-PA025314GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
TUBA8
Alternative Names
Alpha tubulin 8 antibody; Alpha-tubulin 8 antibody; TBA8_HUMAN antibody; Tuba8 antibody; TUBAL2 antibody; Tubulin alpha 8 chain antibody; Tubulin alpha chain like 2 antibody; Tubulin alpha chain-like 2 antibody; Tubulin alpha-8 chain antibody
Species Reactivity
Human,Mouse,Rat
Immunogen
Human TUBA8
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
Gene References into Functions
  1. Data provide evidence for a role of TUBA8 in hepatic fibrogenesis and malignancies making it a novel player in non-alcoholic steatohepatitis and hepatocellular carcinoma pathology. PMID: 28063004
  2. TUBA8 can play a role in the regulation of cell growth, proliferation, and cell migration in a cell-specific manner in vitro. PMID: 21872825
  3. TUBA8 is expressed at low levels in the developing human brain. PMID: 20466094
  4. Mutation of the variant alpha-tubulin TUBA8 results in polymicrogyria with optic nerve hypoplasia. PMID: 19896110
Involvement in disease
Cortical dysplasia, complex, with other brain malformations 8 (CDCBM8)
Subcellular Location
Cytoplasm, cytoskeleton.
Protein Families
Tubulin family
Tissue Specificity
Preferentially expressed in heart, skeletal muscle and testis. Expressed at low levels in the developing brain.
Database Links

HGNC: 12410

OMIM: 605742

KEGG: hsa:51807

STRING: 9606.ENSP00000333326

UniGene: Hs.137400

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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