TUSC5 Antibody

Code CSB-PA062014
Size US$297
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  • Western blot analysis of extracts from LOVO cells, using TUSC5 antibody.
  • Immunofluorescence analysis of HeLa cells, using TUSC5 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TUSC5 Polyclonal antibody
Uniprot No.
Target Names
TUSC5
Alternative Names
TRARG1; IFITMD3; LOST1; TUSC5; Trafficking regulator of GLUT4 1; Dispanin subfamily B member 1; DSPB1; Interferon-induced transmembrane domain-containing protein D3; Protein located at seventeen-p-thirteen point three 1; Tumor suppressor candidate 5
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from internal of Human TUSC5.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB,IF
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
IF 1:100-1:500
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Regulates insulin-mediated adipose tissue glucose uptake and transport by modulation of SLC2A4 recycling. Not required for SLC2A4 membrane fusion upon an initial stimulus, but rather is necessary for proper protein recycling during prolonged insulin stimulation.
Gene References into Functions
  1. Aberrant DNA hypermethylation of TUSC5 in breast cancer suggests epigenetic mechanism of cancer associated down-regulation PMID: 23302999
  2. These findings may point to participation of Tusc5 in shared adipose-nervous system functions. PMID: 17689857
Subcellular Location
Cell membrane; Single-pass membrane protein. Endomembrane system; Single-pass membrane protein. Cytoplasm, perinuclear region.
Protein Families
CD225/Dispanin family
Tissue Specificity
Expressed at high levels in heart, mammary gland, adrenal gland, stomach, smooth muscle and skeletal muscle, and at lower levels in brain and lung. Strongly down-regulated in lung cancer tissues, due to hypermethylation of the corresponding locus. Express
Database Links

HGNC: 29592

OMIM: 612211

KEGG: hsa:286753

STRING: 9606.ENSP00000329548

UniGene: Hs.146059

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