TXLNA Antibody

Code CSB-PA234430
Size US$166
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Image
  • Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-2: A549 cells, 293T cells, Primary antibody: CSB-PA234430(TXLNA Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
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Product Details

Uniprot No.
Target Names
TXLNA
Alternative Names
Alpha-taxilin antibody; DKFZp451J0118 antibody; IL 14 antibody; IL14 antibody; interleukin 14 antibody; MGC11887 antibody; MGC118870 antibody; MGC118871 antibody; RP4-622L5.4 antibody; Taxilin alpha antibody; TXLN antibody; TXLNA antibody; TXLNA_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Fusion protein of Human TXLNA
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
WB 1:500-1:2000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
May be involved in intracellular vesicle traffic and potentially in calcium-dependent exocytosis in neuroendocrine cells.
Gene References into Functions
  1. intrathyroidal production of IL-14 and IL-16 associated with the pathogenesis of autoimmune thyroid disease PMID: 25940130
  2. Silencing of alpha-taxilin expression leads to increased release of infectious hepatitis C virus particles. PMID: 26527738
  3. alpha-taxilin interacts with SNX4 and plays a role in the recycling pathway of TfnR. PMID: 24690921
  4. alpha-taxilin plays an essential role for release of HBV-DNA containing particles. PMID: 23816704
  5. Alpha-taxilin is localized on intracellular components in a syntaxin-independent manner and that the alpha-taxilin-containing intracellular components are associated with the microtubule cytoskeleton. PMID: 22785156
  6. Increased alpha-taxilin protein expression is associated with the metastatic and invasive potential of renal cell cancer. PMID: 21551945
  7. alpha-taxilin may be involved in cell proliferation of hepatocellular carcinoma(HCC), and its expression can be a marker of malignant potential of HCC. PMID: 21042709
  8. identification of isoforms; interaction with syntaxin [alpha-taxilin] PMID: 15184072
  9. role for IL-14alpha (Txln gene product)in the development of both autoimmunity and lymphomagenesis PMID: 17015757
  10. increases in IL-14 transcript levels may play a role in alloantibody formation after renal transplantation PMID: 18645499
  11. IL-14a is important in the pathophysiology of Sjogren's disease PMID: 19038581
  12. analysis of a novel monoclonal antibody against interleukin-14alpha PMID: 19663695

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Protein Families
Taxilin family
Tissue Specificity
Ubiquitous, with much higher expression in heart, kidney, liver and pancreas.
Database Links

HGNC: 30685

OMIM: 608676

KEGG: hsa:200081

STRING: 9606.ENSP00000362711

UniGene: Hs.17987

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