UBE2E2 Antibody

1. changes in methylation rates in umbilical cord samples were associated with the proportion of Firmicutes in the maternal gut PMID: 27863092
2. We investigated the modification of air pollution and diabetes association by a genetic risk score covering 63 T2D genes. Five single variants near GRB14, UBE2E2, PTPRD, VPS26A and KCNQ1 showed nominally significant interactions with PM10 (P<0.05). Our results suggest that genetic risk for T2D may modify susceptibility to air pollution through alterations in insulin sensitivity. PMID: 27281273
3. Ube2e2 underexpression is associated with metabolic diseases. PMID: 27918534
4. After adjustment for age, sex, and BMI, rs163182 in KCNQ1 and rs7612463 in UBE2E2 were found to be associated with Type 2 Diabetes Mellitus risk in Chinese Han population. PMID: 27175665
5. rs7612463 UBE2E2 single nucleotide polymorphism is associated with type 2 diabetes mellitus in a Chinese Han population. PMID: 26020062
6. Study found lack of association between UBE2E2 gene polymorphism (rs7612463) and type 2 diabetes mellitus in a Saudi population PMID: 25337779
7. The genetic variants of UBE2E2 are associated with gestational diabetes mellitus and fasting blood glucose. PMID: 23862583
8. Single nucleotide polymorphism in UBE2E2 is associated with type 2 diabetes. PMID: 20818381
9. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
10. Siah proteins function as E3 ubiquitin-protein ligases PMID: 11786535
11. Ubc8 is a major ISG15-conjugating enzyme responsible for protein ISGylation upon interferon stimulation PMID: 15485925
12. Ubiquitin charging can function as a nuclear import trigger, and identify a novel link between E2 regulation and karyopherin-mediated transport. PMID: 15545318

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HGNC: 12478

OMIM: 602163

KEGG: hsa:7325

STRING: 9606.ENSP00000379931

UniGene: Hs.475688