UBE2W Antibody

Code CSB-PA842638LA01HU
Size US$299
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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) UBE2W Polyclonal antibody
Uniprot No. Q96B02
Target Names UBE2W
Alternative Names FLJ11011 antibody; hUBC 16 antibody; hUBC16 antibody; Probable ubiquitin conjugating enzyme E2 W antibody; Probable ubiquitin-conjugating enzyme E2 W antibody; UBC 16 antibody; UBC-16 antibody; UBC16 antibody; UBE 2W antibody; ube2w antibody; UBE2W_HUMAN antibody; Ubiquitin carrier protein W antibody; Ubiquitin conjugating enzyme 16 antibody; Ubiquitin conjugating enzyme E2 W antibody; Ubiquitin conjugating enzyme E2W antibody; Ubiquitin protein ligase W antibody; Ubiquitin-protein ligase W antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Ubiquitin-conjugating enzyme E2 W protein (1-151AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form Liquid
Tested Applications ELISA
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
(From Uniprot)
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins
Gene References into Functions
  1. Thus, although Rnf4 and Ube2w functionally interact in vitro, these genetic experiments indicate that in response to DNA damage Ube2w and Rnf4 function in distinct pathways. PMID: 27185577
  2. TRIM5alpha requires Ube2W to anchor Lys63-linked ubiquitin chains and restrict reverse transcription. PMID: 26101372
  3. We show the ubequitin-conjugating enzyme (E2) Ube2w uses a unique mechanism to facilitate the specific ubiquitination of the alpha-amino group PMID: 25436519
  4. Ube2w has novel enzymatic properties that direct ubiquitination of the N terminus of substrates PMID: 23696636
  5. UBE2W regulates FANCD2 monoubiquitination by mechanisms different from UBE2T and HRR6. PMID: 21229326
  6. human Ubiquitin-conjugating enzyme (E2) is homologous to the Arabidopsis thaliana UBC-16 gene product and contains 2 nuclear localization signals PMID: 16368532

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Subcellular Location Nucleus
Protein Families Ubiquitin-conjugating enzyme family
Tissue Specificity Widely expressed, with highest expression in brain, liver, pancreas and heart.
Database Links

HGNC: 25616

OMIM: 614277

KEGG: hsa:55284

STRING: 9606.ENSP00000454445

UniGene: Hs.128841

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