UBXN11 Antibody

Code CSB-PA070242
Size US$100
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Product Details

Uniprot No.
Target Names
UBXN11
Alternative Names
COA 1 antibody; colorectal tumor associated antigen 1 antibody; Colorectal tumor associated antigen COA 1 antibody; Colorectal tumor-associated antigen COA-1 antibody; PP2243 antibody; SOC antibody; SOCI antibody; Socius antibody; UBX domain containing 5 antibody; UBX domain containing protein 11 antibody; UBX domain containing protein 5 antibody; UBX domain-containing protein 11 antibody; UBX domain-containing protein 5 antibody; UBX11_HUMAN antibody; UBXD 5 antibody; UBXN11 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of Human Socius.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, IF, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May be involved in the reorganization of actin cytoskeleton mediated by RND1, RND2 AND RND3. Promotes RHOA activation mediated by GNA12 and GNA13.
Gene References into Functions
  1. Socius is a novel Rnd GTPase-interacting protein involved in disassembly of actin stress fibers PMID: 11940653
  2. Both CD4+ and CD8+ T-cell responses against COA-1 can occur in colorectal cancer patients with metastatic disease PMID: 18974390
  3. The rat homolog of UBXD5 promotes RhoA activation through G12/13 heterotrimeric G proteins PMID: 16202387
Subcellular Location
Cytoplasm, cytoskeleton.
Database Links

HGNC: 30600

OMIM: 609151

KEGG: hsa:91544

STRING: 9606.ENSP00000363338

UniGene: Hs.145061

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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