UQCC2 Antibody

Code CSB-PA866268ESR2HU
Size US$166
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Image
  • Western blot
    All lanes: UQCC2 antibody at 3.35 μg/ml
    Lane 1: HepG2 whole cell lysate
    Lane 2: 293T whole cell lysate
    Lane 3: Jurkat whole cell lysate
    Lane 4: A431 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 15 kDa
    Observed band size: 15, 40, 80 kDa

  • Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA866268ESR2HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA866268ESR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) UQCC2 Polyclonal antibody
Uniprot No.
Target Names
UQCC2
Alternative Names
UQCC2 antibody; C6orf125 antibody; MNF1 antibody; Ubiquinol-cytochrome-c reductase complex assembly factor 2 antibody; Breast cancer-associated protein SGA-81M antibody; Mitochondrial nucleoid factor 1 antibody; Mitochondrial protein M19 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Ubiquinol-cytochrome-c reductase complex assembly factor 2 protein (14-126AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex). Plays a role in the modulation of respiratory chain activities such as oxygen consumption and ATP production and via its modulation of the respiratory chain activity can regulate skeletal muscle differentiation and insulin secretion by pancreatic beta-cells. Involved in cytochrome b translation and/or stability.
Gene References into Functions
  1. The function of M19, a novel mitochondrial nucleoid protein, is characterized in muscle and pancreatic beta-cells. PMID: 22363741
  2. M19 associates with the nucleoid and likely regulates the organization and metabolism of mtDNA. PMID: 19643811
Involvement in disease
Mitochondrial complex III deficiency, nuclear 7 (MC3DN7)
Subcellular Location
Mitochondrion matrix, mitochondrion nucleoid. Mitochondrion. Mitochondrion intermembrane space. Mitochondrion matrix. Mitochondrion inner membrane.
Tissue Specificity
Pancreas, skeletal muscle, kidney, liver and heart.
Database Links

HGNC: 21237

OMIM: 614461

KEGG: hsa:84300

STRING: 9606.ENSP00000363348

UniGene: Hs.732448

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