USP45 Antibody

Code CSB-PA025737GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
USP45
Alternative Names
USP45 antibody; Ubiquitin carboxyl-terminal hydrolase 45 antibody; EC 3.4.19.12 antibody; Deubiquitinating enzyme 45 antibody; Ubiquitin thioesterase 45 antibody; Ubiquitin-specific-processing protease 45 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human USP45
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the deubiquitination of SPDL1. Plays a role in the repair of UV-induced DNA damage via deubiquitination of ERCC1, promoting its recruitment to DNA damage sites. May be involved in the maintenance of photoreceptor function. May play a role in normal retinal development. Plays a role in cell migration.
Gene References into Functions
  1. these results establish USP45 as a new regulator of XPF-ERCC1 crucial for efficient DNA repair PMID: 25538220
Subcellular Location
Photoreceptor inner segment. Cytoplasm. Nucleus.
Protein Families
Peptidase C19 family
Tissue Specificity
Widely expressed. High expression is detected in the cerebellum. In the eye, it is expressed at high levels in the optic nerve, sclera and retina, with relatively low levels in the choroid, lens and retinal pigment epithelium.
Database Links

HGNC: 20080

KEGG: hsa:85015

STRING: 9606.ENSP00000333376

UniGene: Hs.143410

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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