USP50 Antibody

Code CSB-PA791798
Size US$297
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  • Western blot analysis of extracts from A549 cells, using USP50 antiobdy.
  • Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using USP50 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) USP50 Polyclonal antibody
Uniprot No.
Target Names
USP50
Alternative Names
USP50 antibody; Inactive ubiquitin carboxyl-terminal hydrolase 50 antibody; Inactive ubiquitin-specific peptidase 50 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthesized peptide derived from C-terminal of Human USP50.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB,IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
IHC 1:50-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Has no peptidase activity.
Gene References into Functions
  1. verexpression of USP50 has no effect on Ku70 mRNA levels, while it reduces Ku70 protein levels by promoting Ku70 degradation, suggesting that USP50 may indirectly regulate Ku70 protein stability. PMID: 29101126
  2. the deubiquitinating enzyme USP50 binds to the ASC protein and subsequently regulates the inflammasome signaling pathway. PMID: 28094437
  3. USP50 may act through a HSP90-dependent mechanism to counteract CDC25B mitotic inducing activity and prevent Wee1 degradation. PMID: 20930503
  4. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
Protein Families
Peptidase C19 family
Tissue Specificity
Weakly expressed in a few tissues.
Database Links

HGNC: 20079

KEGG: hsa:373509

STRING: 9606.ENSP00000434676

UniGene: Hs.677758

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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