UST Antibody, HRP conjugated

Code CSB-PA897525LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) UST Polyclonal antibody
Uniprot No.
Target Names
UST
Alternative Names
2OST antibody; DS2ST antibody; Uronyl 2-sulfotransferase antibody; uronyl-2-sulfotransferase antibody; Ust antibody; UST_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Uronyl 2-sulfotransferase protein (85-183AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Sulfotransferase that catalyzes the transfer of sulfate to the position 2 of uronyl residues. Has mainly activity toward iduronyl residues in dermatan sulfate, and weaker activity toward glucuronyl residues of chondroitin sulfate. Has no activity toward desulfated N-resulfated heparin.
Gene References into Functions
  1. Results show that overexpression of 2OST alone in the HEK293 cells did not appreciably affect heparan sulfate (HS) chain length. Also, its simultaneous overexpression with Hsepi abolished the effect of Hsepi overexpression on the HS chain lengh. PMID: 27511124
  2. Statistical analysis showed the strongest evidence for a variant located in an intron of UST associated with job-related exhaustion. PMID: 23620144
  3. 2OST transfers sulfate preferentially to the GlcA residue located in a unique sequence, -GalNAc(4SO(4))-GlcA-GalNAc(6SO(4))-. PMID: 16192264
  4. analysis of differences and similarities various residues play in the biological roles of the HS-2OST and CS-2OST enzymes PMID: 17227754
Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein Families
Sulfotransferase 3 family
Tissue Specificity
Widely expressed.
Database Links

HGNC: 17223

OMIM: 610752

KEGG: hsa:10090

STRING: 9606.ENSP00000356433

UniGene: Hs.657370

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