UVSSA Antibody, FITC conjugated

1. Data suggest that a common TFIIH subunit p62 recruitment mechanism is shared by UV-stimulated scaffold protein A (UVSSA) in transcription-coupled repair (TCR) and xeroderma pigmentosum, complementation group C protein (XPC) in global genome repair (GGR). PMID: 29069470
2. stabilization of UVSSA by interaction with USP7 is essential for Transcription-coupled Nucleotide Excision Repair PMID: 27129218
3. UVSSA together with USP7 is implicated in regulating transcription-coupled DNA repair.[review] PMID: 23760561
4. Human UVSSA protein is required for the ubiquitination of RNA polymerase and DNA repair after light-induced DNA damage [review]. PMID: 23631307
5. KIAA1530 is an important player in TCR but also lead to a better understanding of the molecular mechanism underlying UV(s)S syndrome. PMID: 22902626
6. Mutations in the UVSSA gene is associated with UV-sensitive syndrome. PMID: 22466610
7. Mutations in UVSSA cause UV-sensitive syndrome and recruits USP7 to regulate transcription-coupled repair. PMID: 22466611
8. Mutations in UVSSA cause UV-sensitive syndrome and destabilize ERCC6 in transcription-coupled DNA repair. PMID: 22466612

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HGNC: 29304

OMIM: 614632

KEGG: hsa:57654

STRING: 9606.ENSP00000374501

UniGene: Hs.380475