VASN Antibody, FITC conjugated

Code CSB-PA025796OC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) VASN Polyclonal antibody
Uniprot No.
Target Names
VASN
Alternative Names
2610528G05Rik antibody; PRO1282 antibody; PRO357 antibody; Protein slit-like 2 antibody; Slit like 2 antibody; Slitl2 antibody; UNQ314 antibody; Vasn antibody; VASN_HUMAN antibody; Vasorin antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Peptide sequence from Human Vasorin protein (553-572AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May act as an inhibitor of TGF-beta signaling.
Gene References into Functions
  1. confirmed for the first time that HepG2-derived VASN can be transferred to human umbilical vein endothelial cells (HUVECs) via receptor mediated endocytosis of exosomes, at least in part through HSPGs PMID: 26157350
  2. results suggest that down-regulation of vasorin expression contributes to neointimal formation after vascular injury and that vasorin modulates cellular responses to pathological stimuli in the vessel wall [vasorin] PMID: 15247411
Subcellular Location
Membrane; Single-pass type I membrane protein. Secreted.
Tissue Specificity
Expressed at highest levels in aorta, at intermediate levels in kidney and placenta and at lowest levels in brain, heart, liver, lung and skeletal muscle. Within the aorta, the strongest expression is found in the tunica media of the proximal ascending ao
Database Links

HGNC: 18517

OMIM: 608843

KEGG: hsa:114990

STRING: 9606.ENSP00000306864

UniGene: Hs.372579

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