VAX1 Antibody

Datasheet

Code	CSB-PA025806LA01HU
Size	US$166
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Image	Western Blot Positive WB detected in: U87 whole cell lysate, 293 whole cell lysate, A549 whole cell lysate All lanes: VAX1 antibody at 3.8µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 35, 22 kDa Observed band size: 35 kDa
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) VAX1 Polyclonal antibody

Uniprot No.

Q5SQQ9

Target Names

VAX1

Alternative Names

VAX1 antibody; Ventral anterior homeobox 1 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Ventral anterior homeobox 1 protein (2-106AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The VAX1 Antibody (Product code: CSB-PA025806LA01HU) is Non-conjugated. For VAX1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA025806LB01HU	VAX1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA025806LC01HU	VAX1 Antibody, FITC conjugated
Biotin	CSB-PA025806LD01HU	VAX1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Transcription factor that may function in dorsoventral specification of the forebrain. Required for axon guidance and major tract formation in the developing forebrain. May contribute to the differentiation of the neuroretina, pigmented epithelium and optic stalk.

Gene References into Functions

rs4752028 weakly associated with nonsyndromic cleft lip with or without cleft palate in northern Chinese Han population PMID: 28383424
Our study replicated previous GWAS findings for markers in VAX1 in the Asian population, and identified rare variants in PAX7 and VAX1 that may contribute to the etiology of CL(P). PMID: 23463464
VAX1 rs10787760, rs6585429 and rs1871345 polymorphisms may be involved in nonsyndromic cleft lip with or without cleft palate in Brazilian patients, but there is no association with polymorphisms in FGF12, VCL, or CX43 PMID: 23679094
The data do not support the hypothesis that highly penetrant rare variants in VAX1 are a cause of nonsyndromic cleft lip with or without cleft palate. PMID: 23081944
This is the first description of a patient with a VAX1 mutation and establishes VAX1 as a new causative gene for anophthalmia/microphthalmia (A/M) in humans. PMID: 22095910

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Involvement in disease

Microphthalmia, syndromic, 11 (MCOPS11)

Subcellular Location

Nucleus.

Protein Families

EMX homeobox family

Database Links

HGNC: 12660

OMIM: 604294

KEGG: hsa:11023

STRING: 9606.ENSP00000358207

UniGene: Hs.441536

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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