VAX2 Antibody

Code CSB-PA025807LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: Hela whole cell lysate, A549 whole cell lysate
    All lanes: VAX2 antibody at 1:2000
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 31 kDa
    Observed band size: 31 kDa

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) VAX2 Polyclonal antibody
Uniprot No.
Target Names
VAX2
Alternative Names
VAX2 antibody; Ventral anterior homeobox 2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Ventral anterior homeobox 2protein (1-74AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The VAX2 Antibody (Product code: CSB-PA025807LA01HU) is Non-conjugated. For VAX2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA025807LB01HU VAX2 Antibody, HRP conjugated ELISA
FITC CSB-PA025807LC01HU VAX2 Antibody, FITC conjugated
Biotin CSB-PA025807LD01HU VAX2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Transcription factor that may function in dorsoventral specification of the forebrain. Regulates the expression of Wnt signaling antagonists including the expression of a truncated TCF7L2 isoform that cannot bind CTNNB1 and acts therefore as a potent dominant-negative Wnt antagonist. Plays a crucial role in eye development and, in particular, in the specification of the ventral optic vesicle. May be a regulator of axial polarization in the retina.
Gene References into Functions
  1. Although inappropriate promoter methylation was not invariantly associated with reduced transcript expression, a significant association was apparent for the ARHGEF4, PON3, STAT5a, and VAX2 gene transcripts (P<0.05). Herein, we present the first genome-wide DNA methylation analysis in a unique HG-NMIBC cohort, showing extensive and discrete methylation changes relative to normal bladder and low-intermediate-grade tumor PMID: 26929985
  2. A susceptibility locus was identified with lead single nucleotide polymorphism rs3771395 on chromosome 2p13.3 (meta-analysis, P = 1.97 x 10(-7)) in the VAX2 gene for astigmatism. PMID: 23322567
Subcellular Location
Nucleus.
Protein Families
EMX homeobox family
Database Links

HGNC: 12661

OMIM: 604295

KEGG: hsa:25806

STRING: 9606.ENSP00000234392

UniGene: Hs.249170

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