VMP1 Antibody, HRP conjugated

Datasheet
Code CSB-PA856940LB01HU
Size US$299
Uniprot No. Q96GC9
Immunogen Recombinant Human Vacuole membrane protein 1 protein (136-235AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis. Plays a role in the initial stages of the autophagic process through its interaction with BECN1 (By similarity). Involved in cell-cell adhesion. Plays an essential role in formation of cell junctions.
Form Liquid
Conjugate HRP
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Vacuole membrane protein 1 (Transmembrane protein 49), VMP1, TDC1 TMEM49
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Research Area Cancer
Target Names VMP1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis. Plays a role in the initial stages of the autophagic process through its interaction with BECN1 (By similarity). Involved in cell-cell adhesion. Plays an essential role in formation of cell junctions.
Subcellular Location Endoplasmic reticulum-Golgi intermediate compartment membrane, Multi-pass membrane protein, Cell membrane, Multi-pass membrane protein, Vacuole membrane, Multi-pass membrane protein, Endoplasmic reticulum
Protein Families VMP1 family
Database Links

HGNC: 29559

OMIM: 611753

KEGG: hsa:81671

STRING: 9606.ENSP00000262291

UniGene: Hs.444569

Pathway Autophagy

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