VP40 Antibody, Biotin conjugated

Code CSB-PA810348HD01RCJ
Size US$166
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Product Details

Full Product Name
Rabbit anti-Reston ebolavirus (strain Reston-89) (REBOV) (Reston Ebola virus) VP40 Polyclonal antibody
Uniprot No.
Target Names
VP40
Alternative Names
VP40Matrix protein VP40 antibody; Membrane-associated protein VP40 antibody
Raised in
Rabbit
Species Reactivity
Reston ebolavirus
Immunogen
Recombinant Reston ebolavirus Matrix protein VP40 protein (1-331AA)
Immunogen Species
Reston ebolavirus (strain Reston-89) (REBOV) (Reston Ebola virus)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Plays an essential role virus particle assembly and budding. Acts by interacting with viral ribonucleocapsid and host members of the ESCRT (endosomal sorting complex required for transport) system such as host VPS4, PDCD6IP/ALIX, NEDD4 or TGS101. The interaction with host E3 ubiquitin ligase SMURF2 also facilitates virus budding. May play a role in immune cell dysfunction by being packaged into exosomes that can decrease the viability of recipient cells (via RNAi suppression and exosome-bystander apoptosis).
Gene References into Functions
  1. Hexameric model of VP40 using X-ray and electron microscopy was presented. PMID: 15908231
Subcellular Location
Virion membrane; Peripheral membrane protein. Host late endosome membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Host endomembrane system; Peripheral membrane protein.
Protein Families
Filoviridae matrix protein VP40 family
Database Links

KEGG: vg:955192

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