VWA5A Antibody

Code CSB-PA000991
Size US$100
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  • Western Blot analysis of 293 cells using BCSC-1 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
VWA5A
Alternative Names
VWA5A antibody; BCSC1 antibody; LOH11CR2A antibody; von Willebrand factor A domain-containing protein 5A antibody; Breast cancer suppressor candidate 1 antibody; BCSC-1 antibody; Loss of heterozygosity 11 chromosomal region 2 gene A protein antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of Human BCSC-1.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May play a role in tumorigenesis as a tumor suppressor. Altered expression of this protein and disruption of the molecular pathway it is involved in, may contribute directly to or modify tumorigenesis.
Gene References into Functions
  1. BCSC-1 binds to Sox10, which down regulates MITF, and results in a switch of melanoma cells from a proliferative to a migratory phenotype. PMID: 22594792
  2. LOH11CR2A, PIG8 and CHEK1 are candidate tumor suppressor genes associated with breast carcinoma and have significant clinical as well as prognostic importance. PMID: 21803008
  3. BCSC-1 suppression might play roles in tumorigenesis of some nasopharyngeal carcinomas PMID: 19656157
Tissue Specificity
Expressed at low level in many tissues. Not expressed in 80% of tumor cell lines tested.
Database Links

HGNC: 6658

OMIM: 602929

KEGG: hsa:4013

STRING: 9606.ENSP00000376504

UniGene: Hs.152944

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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