YPEL3 Antibody

Code CSB-PA026272LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA026272LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) YPEL3 Polyclonal antibody
Uniprot No.
Target Names
YPEL3
Alternative Names
Protein yippee-like 3 antibody; Small ubiquitinated apoptotic protein antibody; Yippee like 3 antibody; Yippee-like 3 (Drosophila) antibody; Ypel3 antibody; YPEL3_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Protein yippee-like 3 protein (1-119AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The YPEL3 Antibody (Product code: CSB-PA026272LA01HU) is Non-conjugated. For YPEL3 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA026272LB01HU YPEL3 Antibody, HRP conjugated ELISA
FITC CSB-PA026272LC01HU YPEL3 Antibody, FITC conjugated
Biotin CSB-PA026272LD01HU YPEL3 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Involved in proliferation and apoptosis in myeloid precursor cells.
Gene References into Functions
  1. Expression of the YPEL3 gene was upregulated in human colonic adenocarcinoma tissue. PMID: 29988027
  2. Data show that YPEL3 is downregulated in nasopharyngeal carcinoma (NPC) cell lines and tissue samples and it suppresses NPC EMT and metastasis by suppressing the Wnt/beta-catenin signaling pathway. PMID: 27400785
  3. YPEL3 expression, which is induced by the removal of estrogen or treatment with tamoxifen triggers cellular senescence in MCF-7 cells while loss of YPEL3 increases the growth rate of MCF-7 cells. PMID: 21671470
  4. YPEL3 is downregulated in colon tumors. PMID: 21267786
  5. In this review we show that transcriptionally active forms of p73 and p63, family members of p53, can transactivate the human YPEL3 gene[review] PMID: 21196260
  6. Findings point to YPEL3 being a novel tumor suppressor, which upon induction triggers a permanent growth arrest in human tumor and normal cells. PMID: 20388804

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Subcellular Location
Nucleus, nucleolus.
Protein Families
Yippee family
Tissue Specificity
Widely expressed.
Database Links

HGNC: 18327

OMIM: 609724

KEGG: hsa:83719

STRING: 9606.ENSP00000381821

UniGene: Hs.513491

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