ZC4H2 Antibody

Datasheet

Code	CSB-PA873628LA01HU
Size	US$166
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Image	Western Blot Positive WB detected in: Mouse spleen tissue All lanes: ZC4H2 antibody at 3μg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 27, 16, 24, 21, 26 kDa Observed band size: 27 kDa Immunofluorescent analysis of Hela cells using CSB-PA873628LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ZC4H2 Polyclonal antibody

Uniprot No.

Q9NQZ6

Target Names

ZC4H2

Alternative Names

HCA127 antibody; Hepatocellular carcinoma-associated antigen 127 antibody; KIAA1166 antibody; OTTHUMP00000023432 antibody; Zc4h2 antibody; ZC4H2_HUMAN antibody; Zinc finger C4H2 domain containing antibody; Zinc finger C4H2 domain-containing protein antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Zinc finger C4H2 domain-containing protein (1-224AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The ZC4H2 Antibody (Product code: CSB-PA873628LA01HU) is Non-conjugated. For ZC4H2 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA873628LB01HU	ZC4H2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA873628LC01HU	ZC4H2 Antibody, FITC conjugated
Biotin	CSB-PA873628LD01HU	ZC4H2 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IF

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IF	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Plays a role in interneurons differentiation. Involved in neuronal development and in neuromuscular junction formation.

Gene References into Functions

The present patient confirms that female carriers can also be severely affected. Systematic clinical investigations of both males and females are needed to define the variety in nature and severity of phenotypes related to ZC4H2 variants. PMID: 28345801
ZC4H2, an XLID gene, is required for the generation of a specific subset of CNS interneurons PMID: 26056227
ZC4H2 mutations are associated with arthrogryposis multiplex congenita and intellectual disability through impairment of central and peripheral synaptic plasticity. PMID: 23623388

Involvement in disease

Wieacker-Wolf syndrome (WRWF)

Subcellular Location

Cytoplasm. Nucleus. Cell junction, synapse, postsynaptic cell membrane. Note=Upon transfection into mouse primary hippocampal neurons, localizes at excitatory, but not inhibitory, postsynaptic sites.

Tissue Specificity

Expressed in fetal tissues, including in brain, intestine, lung, kidney and muscle. Isoform 1 is expressed in numerous fetal brain regions. Isoform 3 is highly expressed in numerous fetal brain regions and spinal cord.

Database Links

HGNC: 24931

OMIM: 300897

KEGG: hsa:55906

STRING: 9606.ENSP00000363972

UniGene: Hs.28249

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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