ZC4H2 Antibody

Code CSB-PA873628LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: Mouse spleen tissue
    All lanes: ZC4H2 antibody at 3μg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 27, 16, 24, 21, 26 kDa
    Observed band size: 27 kDa

  • Immunofluorescent analysis of Hela cells using CSB-PA873628LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ZC4H2 Polyclonal antibody
Uniprot No.
Target Names
ZC4H2
Alternative Names
HCA127 antibody; Hepatocellular carcinoma-associated antigen 127 antibody; KIAA1166 antibody; OTTHUMP00000023432 antibody; Zc4h2 antibody; ZC4H2_HUMAN antibody; Zinc finger C4H2 domain containing antibody; Zinc finger C4H2 domain-containing protein antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Zinc finger C4H2 domain-containing protein (1-224AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The ZC4H2 Antibody (Product code: CSB-PA873628LA01HU) is Non-conjugated. For ZC4H2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA873628LB01HU ZC4H2 Antibody, HRP conjugated ELISA
FITC CSB-PA873628LC01HU ZC4H2 Antibody, FITC conjugated
Biotin CSB-PA873628LD01HU ZC4H2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IF
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
Plays a role in interneurons differentiation. Involved in neuronal development and in neuromuscular junction formation.
Gene References into Functions
  1. The present patient confirms that female carriers can also be severely affected. Systematic clinical investigations of both males and females are needed to define the variety in nature and severity of phenotypes related to ZC4H2 variants. PMID: 28345801
  2. ZC4H2, an XLID gene, is required for the generation of a specific subset of CNS interneurons PMID: 26056227
  3. ZC4H2 mutations are associated with arthrogryposis multiplex congenita and intellectual disability through impairment of central and peripheral synaptic plasticity. PMID: 23623388
Involvement in disease
Wieacker-Wolf syndrome (WRWF)
Subcellular Location
Cytoplasm. Nucleus. Cell junction, synapse, postsynaptic cell membrane. Note=Upon transfection into mouse primary hippocampal neurons, localizes at excitatory, but not inhibitory, postsynaptic sites.
Tissue Specificity
Expressed in fetal tissues, including in brain, intestine, lung, kidney and muscle. Isoform 1 is expressed in numerous fetal brain regions. Isoform 3 is highly expressed in numerous fetal brain regions and spinal cord.
Database Links

HGNC: 24931

OMIM: 300897

KEGG: hsa:55906

STRING: 9606.ENSP00000363972

UniGene: Hs.28249

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