ZMIZ1 Antibody, Biotin conjugated

Datasheet
Code CSB-PA890749LD01HU
Size US$299
Uniprot No. Q9ULJ6
Immunogen Recombinant Human Zinc finger MIZ domain-containing protein 1 protein (405-559AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Acts as transcriptional coactivator. Increases ligand-dependent transcriptional activity of AR and promotes AR sumoylation. The stimulation of AR activity is dependent upon sumoylation (PubMed:14609956, PubMed:26522984). Involved in transcriptional activation of a subset of NOTCH1 target genes including MYC. Involved in thymocyte and T cell development (By similarity).
Form Liquid
Conjugate Biotin
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Zinc finger MIZ domain-containing protein 1 (PIAS-like protein Zimp10) (Retinoic acid-induced protein 17), ZMIZ1, KIAA1224 RAI17 ZIMP10
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Research Area Cell Biology
Target Names ZMIZ1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Acts as transcriptional coactivator. Increases ligand-dependent transcriptional activity of AR and promotes AR sumoylation. The stimulation of AR activity is dependent upon sumoylation
Subcellular Location Nucleus speckle, Cytoplasm
Tissue Specificity Expressed most abundantly in ovary and, at lower levels, in prostate, spleen and testis. Weak expression, if any, in thymus, small intestine, colon and peripheral blood leukocytes.
Database Links

HGNC: 16493

OMIM: 607159

KEGG: hsa:57178

STRING: 9606.ENSP00000334474

UniGene: Hs.193118

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