ZNF143 Antibody

1. The zinc finger, ZNF143, binds to the CCCAGCAG site in the CEBPA promoter. PMID: 28900037
2. The inhibition of ZNF143 activity by small molecules induced tumor regression. PMID: 28192620
3. Data show that zinc finger protein 143 (ZNF143) promotes epithelial-mesenchymal transition (EMT) through regulating PI3K/AKT pathway in gastric cancer (GC) cells. PMID: 27449034
4. The results show that as an important partner of CTCF, ZNF143 helps establishing the conserved chromatin structure by cooperating with cohesin. PMID: 27414788
5. ZNF143 is directly recruited to the promoter of genes engage in chromatin interactions, where it binds to its DNA recognition sequence. PMID: 25645053
6. THAP11, ZNF143, and HCF-1 form a mutually dependent complex on chromatin, which is independent of E2F occupancy. PMID: 25437553
7. ZNF143 expresses different 3'-untranslated regions (3'-UTR) as a result of alternative polyadenylation PMID: 24952353
8. High zinc-finger protein 143 is associated with cancer cell migration and invasion through ZEB1 and E-cadherin in colon cancer. PMID: 24009065
9. ZNF143 upregulated GPX1 activity and protecting cells from oxidative damage. PMID: 23152058
10. GIPC is involved in IGF-1 signaling leading to ZNF143 expression through the regulation of ROS production, which may play a role for colon cancer tumorigenesis. PMID: 21909943
11. The data provides the demonstration that hStaf/ZNF143 is indeed a transcription factor controlling the expression of divergent protein-protein and protein-non-coding RNA gene pairs. PMID: 21177654
12. data suggest that IGF-1 induces ZNF143 expression in cancer cells via PI3-kinase and reactive oxygen species generation during receptor internalization. PMID: 20733350
13. ZNF143 might be a master regulator of the cell cycle. PMID: 20860770
14. These results demonstrated that the Staf binding site functioned as the basal transcriptional activator of the S phase-specific gene ESCO2, but other mechanisms are required for cell cycle-dependent expression. PMID: 20116366
15. human interferon regulatory factor-3 (IRF-3) gene promoter contains a functional SPH element that is bound by SBF/Staf in vitro and in transfected cells PMID: 11724783
16. ZNF143 plays a key role in basal and tissue-specific expression of transaldolase and regulation of the metabolic network controlling cell survival and differentiation PMID: 14702349
17. interplay of ZNF143, p73 and ZNF143 target genes is involved in DNA repair gene expression and cisplatin resistance PMID: 17297437
18. A pivotal role for transcription factor hStaf/ZNF143 in the expression of the BUB1B gene was demonstrated. PMID: 17478512
19. Transcription factor ZNF143 is required for expression of TFAM gene. PMID: 17707600
20. Staf activates U6 transcription from a preassembled chromatin template in vitro and associates with several proteins linked to chromatin modification, among them chromodomain-helicase-DNA binding protein 8 (CHD8). PMID: 17938208

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HGNC: 12928

OMIM: 603433

KEGG: hsa:7702

STRING: 9606.ENSP00000379847

UniGene: Hs.523471