ZNF281 Antibody

Datasheet

Code	CSB-PA026637LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA026637LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ZNF281 Polyclonal antibody

Uniprot No.

Q9Y2X9

Target Names

ZNF281

Alternative Names

GC box binding zinc finger protein 1 antibody; GC-box-binding zinc finger protein 1 antibody; GZP1 antibody; Transcription factor ZBP-99 antibody; ZBP 99 antibody; ZBP99 antibody; zfp281 antibody; Zinc finger DNA binding protein 99 antibody; Zinc finger DNA-binding protein 99 antibody; Zinc finger protein 281 antibody; ZN281_HUMAN antibody; ZNF281 antibody; ZNP 99 antibody; ZNP 99 transcription factor antibody; ZNP99 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Zinc finger protein 281 protein (1-300AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The ZNF281 Antibody (Product code: CSB-PA026637LA01HU) is Non-conjugated. For ZNF281 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA026637LB01HU	ZNF281 Antibody, HRP conjugated	ELISA
FITC	CSB-PA026637LC01HU	ZNF281 Antibody, FITC conjugated
Biotin	CSB-PA026637LD01HU	ZNF281 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Transcription repressor that plays a role in regulation of embryonic stem cells (ESCs) differentiation. Required for ESCs differentiation and acts by mediating autorepression of NANOG in ESCs: binds to the NANOG promoter and promotes association of NANOG protein to its own promoter and recruits the NuRD complex, which deacetylates histones. Not required for establishement and maintenance of ESCs. Represses the transcription of a number of genes including GAST, ODC1 and VIM. Binds to the G-rich box in the enhancer region of these genes.

Gene References into Functions

These observations suggest that ZNF281 is a controller of neuronal differentiation that should be evaluated as a prognostic marker in neuroblastoma. PMID: 29941555
involvement of ZNF281 in the cellular response to genotoxic stress through the control exercised on the expression of genes that act in different repair mechanisms PMID: 26300006
High ZNF281 expression is associated with colon and breast cancer. PMID: 24185900

Subcellular Location

Nucleus.

Protein Families

Krueppel C2H2-type zinc-finger protein family

Database Links

HGNC: 13075

KEGG: hsa:23528

STRING: 9606.ENSP00000294740

UniGene: Hs.59757

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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