ZXDC Antibody

Code CSB-PA027161GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
ZXDC
Alternative Names
ZXDC antibody; ZXDL antibody; Zinc finger protein ZXDC antibody; ZXD-like zinc finger protein antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Human ZXDC
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IF
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes.
Gene References into Functions
  1. Data show that ZXDC1 is a regulator in the process of myeloid function and that ZXDC1 is responsible for Ccl2 gene de-repression by BCL6. PMID: 23954399
  2. Role of ZXD proteins in regulating MHC II transcription. PMID: 19777325
  3. ZXDC is an important regulator of both MHC class I and class II transcription PMID: 16600381
  4. ZXDA and ZXDC form an important regulatory complex for MHC II gene transcription. PMID: 17493635
  5. study found sumoylation does not appear to disrupt or modulate interaction of ZXDC with binding partners; sumoylation of ZXDC is required for full activity of transcriptional activation domain; study suggests sumoylation is an important regulator of ZXDC PMID: 17696781

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Subcellular Location
Nucleus.
Protein Families
ZXD family
Tissue Specificity
Expressed at high levels in heart, kidney, liver and testis, at moderate levels in brain and stomach, and at low levels in lung, muscle, placenta, small intestine and spleen.
Database Links

HGNC: 28160

OMIM: 615746

KEGG: hsa:79364

STRING: 9606.ENSP00000374359

UniGene: Hs.440049

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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