grxD Antibody

Code CSB-PA359726XA11ENV
Size US$166
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Image
  • Western Blot
    Positive WB detected in: recombinant protein
    All lanes: grxD Antibody at 1:1000
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 35 kDa
    Observed band size: 35 kDa
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Product Details

Uniprot No.
Target Names
grxD
Alternative Names
Glutaredoxin 4 (Grx4) (Monothiol glutaredoxin), grxD, ydhD
Species Reactivity
E.coli
Immunogen
Recombinant E.coli grxD protein (24-115aa)
Immunogen Species
Escherichia coli(strain K12)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Affinity-chromatography
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Description

The grxD polyclonal antibody is produced by introducing the recombinant E.coli grxD protein (amino acids 24-115) into a rabbit, stimulating the generation of antibodies targeting this antigen. A booster injection is administered to enhance antibody production, followed by the collection and purification of serum containing grxD polyclonal antibodies using affinity chromatography. Extensive testing through ELISA and WB assays has verified the antibody's ability to specifically recognize E.coli grxD protein.

The E. coli grxD protein is a thiol-disulfide oxidoreductase that plays a crucial role in maintaining cellular redox balance and protecting the cell from oxidative stress. Specifically, grxD is involved in Thiol-Disulfide exchange, reduction of protein disulfides, detoxification of reactive oxygen species (ROS), and repair and maintenance of Fe-S clusters in proteins.

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Target Background

Function
Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters.
Gene References into Functions
  1. GrxD has roles as a component of both homodimeric and heterodimeric complexes PMID: 21899261
Subcellular Location
Cytoplasm.
Protein Families
Glutaredoxin family, Monothiol subfamily
Database Links
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