lktA Antibody

Code CSB-PA314743EA01ESE
Size US$299
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Product Details

Full Product Name Rabbit anti-Mannheimia haemolytica lktA Polyclonal antibody
Uniprot No. P0C085
Target Names lktA
Alternative Names lktA antibody; Leukotoxin antibody; Lkt antibody
Raised in Rabbit
Species Reactivity Mannheimia haemolytica
Immunogen Recombinant Mannheimia haemolytica Leukotoxin protein (715-953AA)
Immunogen Species Mannheimia haemolytica
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form Liquid
Tested Applications ELISA
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Applications : WB

Sample type: goats and lambs

Review: Mannheimia haemolytica (Mha) culture growth and Lkt secretion profile. (a): SDS page of Mha culture supernatant samples. (b): Anti-Lkt Western blot of Mha culture supernatant samples. SM: Molecular weight marker(color protein standard broad range P7712S Biolabs).

By Anonymous

Target Background

(From Uniprot)
Pasteurella leukotoxins are exotoxins that attack host leukocytes and especially polymorphonuclear cells, by causing cell rupture. The leukotoxin binds to the host LFA-1 integrin and induces a signaling cascade leading to many biological effects, including tyrosine phosphorylation of the CD18 tail, elevation of the intracellular Ca(2+) and lysis of the host cell (By similarity). This leukotoxin is a major contributor to the pathogenesis of lung injury in ovine pneumonic pasteurellosis. It has also weak hemolytic activity.
Subcellular Location Secreted, Host cell membrane, Multi-pass membrane protein
Protein Families RTX prokaryotic toxin (TC 1.C.11) family


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