ptsH Antibody, Biotin conjugated

Datasheet

Code	CSB-PA362538HD01BRJ
Size	US$166
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Target Background

Product Details

Full Product Name

Rabbit anti-Bacillus subtilis (strain 168) ptsH Polyclonal antibody

Uniprot No.

P08877

Target Names

ptsH

Alternative Names

ptsH antibody; BSU13900 antibody; Phosphocarrier protein HPr antibody; Histidine-containing protein antibody

Raised in

Rabbit

Species Reactivity

Bacillus subtilis

Immunogen

Recombinant Bacillus subtilis Phosphocarrier protein HPr protein (2-88AA)

Immunogen Species

Bacillus subtilis (strain 168)

Conjugate

Biotin

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function

General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.; P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity.

Gene References into Functions

Results show that in addition to the phosphorylase activity of the HPr kinase/phosphorylase, the serine/threonine protein phosphatase PrpC uses HPr(Ser-P) as a target. PMID: 17693724

Subcellular Location

Cytoplasm.

Protein Families

HPr family

Database Links

KEGG: bsu:BSU13900

STRING: 224308.Bsubs1_010100007716

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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