rgpA Antibody

Name: rgpA Antibody
Brand: CUSABIO
SKU: CSB-PA338957LA01PQP

^{Rare Species}

Datasheet

Citations (3)

Code	CSB-PA338957LA01PQP
Size	US$166
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Product Details
Citations
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Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Porphyromonas gingivalis rgpA Polyclonal antibody

Uniprot No.

P28784

Target Names

rgpA

Alternative Names

rgpA antibody; rgp1Gingipain R1 antibody; EC 3.4.22.37 antibody; Arg-gingipain antibody; Gingipain 1 antibody; RGP-1 antibody

Raised in

Rabbit

Species Reactivity

Porphyromonas gingivalis

Immunogen

Recombinant Porphyromonas gingivalis Gingipain R1 protein (228-720AA)

Immunogen Species

Porphyromonas gingivalis

Conjugate

Non-conjugated

The rgpA Antibody (Product code: CSB-PA338957LA01PQP) is Non-conjugated. For rgpA Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA338957LB01PQP	rgpA Antibody, HRP conjugated	ELISA
FITC	CSB-PA338957LC01PQP	rgpA Antibody, FITC conjugated
Biotin	CSB-PA338957LD01PQP	rgpA Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Description

The CSB-PA338957LA01PQP polyclonal antibody against rgpA was generated by immunizing rabbits with recombinant Porphyromonas gingivalis Gingipain R1 protein (228-720aa). RgpA is a thiol protease that works synergistically with RgpB to catalyze the maturation of fimbrial subunits such as FimA. It plays a significant role in periodontal tissue destruction and evasion of host defense mechanisms, requiring cysteine for activation and Ca²⁺ and/or Mg²⁺ for stabilization.

The rabbit anti-Porphyromonas gingivalis rgpA polyclonal antibody was purified by protein G, reaching a 95% purity level. It specifically binds to rgpA proteins of Porphyromonas gingivalis and can detect endogenous levels of rgpA protein in ELISA assays.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Citations

Porphyromonas gingivalis aggravates atherosclerotic plaque instability by promoting lipid-laden macrophage necroptosis X Huang, M Xie, Y Wang, X Lu, F Mei,Signal Transduction and Targeted Therapy,2025
Intraperitoneal Injection of the Porphyromonas gingivalis Outer Membrane Vesicle (OMV) Stimulated Expressions of Neuroinflammatory Markers and Histopathological Changes in the Brains of Adult Zebrafish M Adewoyin, A Hamarsha, R Akinsola, SL Teoh,International Journal of Molecular Sciences,2024
A Single Dose Intraperitoneal Injection of P. gingivalis Outer Membrane Vesicle (OMV) Stimulated Expressions of Neuroinflammatory Markers and Histopathological Changes in the Brain of Adult Zebrafish M Adewoyin, H Mohamed, R Akinsola, SL Teoh,Medicine and Pharmacology, Neuroscience and Neurology,2024

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Target Background

Function

Thiol protease. Acts synergistically with RgpB to catalyze the maturation of fimbrial subunits, such as FimA. Its proteolytic activity is a major factor in both periodontal tissue destruction and in evasion of host defense mechanisms (Probable).

Subcellular Location

Secreted.

Protein Families

Peptidase C25 family

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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Target Therapy

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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