rgpA Antibody

Code CSB-PA338957LA01PQP
Size US$166
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Product Details

Full Product Name
Rabbit anti-Porphyromonas gingivalis rgpA Polyclonal antibody
Uniprot No.
Target Names
rgpA
Alternative Names
rgpA antibody; rgp1Gingipain R1 antibody; EC 3.4.22.37 antibody; Arg-gingipain antibody; Gingipain 1 antibody; RGP-1 antibody
Raised in
Rabbit
Species Reactivity
Porphyromonas gingivalis
Immunogen
Recombinant Porphyromonas gingivalis Gingipain R1 protein (228-720AA)
Immunogen Species
Porphyromonas gingivalis
Conjugate
Non-conjugated

The rgpA Antibody (Product code: CSB-PA338957LA01PQP) is Non-conjugated. For rgpA Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA338957LB01PQP rgpA Antibody, HRP conjugated ELISA
FITC CSB-PA338957LC01PQP rgpA Antibody, FITC conjugated
Biotin CSB-PA338957LD01PQP rgpA Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Description

The CSB-PA338957LA01PQP polyclonal antibody against rgpA was generated by immunizing rabbits with recombinant Porphyromonas gingivalis Gingipain R1 protein (228-720aa). RgpA is a thiol protease that works synergistically with RgpB to catalyze the maturation of fimbrial subunits such as FimA. It plays a significant role in periodontal tissue destruction and evasion of host defense mechanisms, requiring cysteine for activation and Ca2+ and/or Mg2+ for stabilization.

The rabbit anti-Porphyromonas gingivalis rgpA polyclonal antibody was purified by protein G, reaching a 95% purity level. It specifically binds to rgpA proteins of Porphyromonas gingivalis and can detect endogenous levels of rgpA protein in ELISA assays.

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Target Background

Function
Thiol protease. Acts synergistically with RgpB to catalyze the maturation of fimbrial subunits, such as FimA. Its proteolytic activity is a major factor in both periodontal tissue destruction and in evasion of host defense mechanisms (Probable).
Subcellular Location
Secreted.
Protein Families
Peptidase C25 family
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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