wnt8 Antibody

1. Data show that Noggin4 fine-tune the Wnt8 posterior-to-anterior gradient. PMID: 26973133
2. EFHC1 domains are involved in ciliary localization, ciliogenesis, and the regulation of Wnt8a signaling PMID: 26783883
3. Sulf1 inhibits the ability of Wnt8a to activate the canonical Wnt signalling pathway. PMID: 25681501
4. study presents the structure of Xenopus Wnt8 (XWnt8) in complex with the mouse Fz8-cysteine-rich domain to a resolution of 3.25 A PMID: 22653731
5. Xwnt8 directly initiates expression of labial Hox genes. PMID: 19623617
6. Wnt8 conveyed by Frizzled-related proteins can activate canonical Wnt signalling despite the function of Frizzled-related proteins as Wnt inhibitors, suggesting a novel regulatory system for Wnts by sFRPs PMID: 19906850
7. by performing gain- and loss-of-function of Wnt signaling experiments, we show that this pathway plays an important role not only in neural crest induction but also in the specification of the neural crest competence territory PMID: 14699582
8. Wnt8 may stimulate a cellular phosphatase to dephosphorylate and activate CKIepsilon PMID: 14722104
9. Molecular modeling of the complex between the xWNT8 protein and the CRD domain of mFZD8 PMID: 17506343
10. Xwnt8-mediated posteriorization is restricted to the eye level and is independent of mesoderm formation. PMID: 18318733
11. Fgf8a induces neural crest (NC) indirectly through the activation of Wnt8 in the paraxial mesoderm, which in turn promotes NC formation in the overlying ectoderm primed by Bmp antagonists. PMID: 18997112

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KEGG: xla:397970

UniGene: Xl.49