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Recombinant ABC transporter ced-7 (ced-7), partial

Recombinant ABC transporter ced-7 (ced-7), partial

Code	CSB-YP333886CXY
MSDS	MSDS
Size	Pls inquire
Source	Yeast
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Code	CSB-EP333886CXY
MSDS	MSDS
Size	Pls inquire
Source	E.coli
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Code	CSB-EP333886CXY-B
MSDS	MSDS
Size	Pls inquire
Source	E.coli
Conjugate	Avi-tag Biotinylated E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code	CSB-BP333886CXY
MSDS	MSDS
Size	Pls inquire
Source	Baculovirus
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Code	CSB-MP333886CXY
MSDS	MSDS
Size	Pls inquire
Source	Mammalian cell
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

ced-7

Uniprot No.

P34358

Alternative Names

ced-7; C48B4.4ABC transporter ced-7; Cell death protein 7

Species

Caenorhabditis elegans

Protein Length

Partial

Tag Info

Tag type will be determined during the manufacturing process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Form

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Buffer before Lyophilization

Tris/PBS-based buffer, 6% Trehalose, pH 8.0

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Troubleshooting and FAQs

Protein FAQs

Storage Condition

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Lead Time

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Datasheet

Please contact us to get it.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Functions in the engulfment of cell corpses during embryonic programmed cell death to translocate molecules that mediate homotypic adhesion between cell surfaces of the dying and engulfing cells.

Gene References into Functions

The results reveal the existence of a WLDS/Nmnat-independent axonal degeneration pathway in C. elegans, conservation of the axonal clearance machinery, and a function for CED-7 and NRF-5 in this process. PMID: 26876181
CED-7 and TTR-52 may promote the efflux of phosphatidylserine (PS) from apoptotic cells through the generation of extracellular PS vesicles, which lead to exoplasmic leaflet (exPS) expression on phagocytes via TTR-52 and CED-1 to facilitate cell corpse clearance. PMID: 22727702
Review. CED-7 is akey player in engulfment. Its mode of action is unusual in the panorama of engulfment receptors since they act as lipid transporters. Loss of CED-7 has phenotypic consequences exclusively on engulfment. PMID: 16471259

Subcellular Location

Membrane; Multi-pass membrane protein.

Protein Families

ABC transporter superfamily, ABCA family

Tissue Specificity

Ubiquitous in embryos. Expressed in larval germline precursors. Expression in larvae and adults is seen in amphid sheath cells, pharyngeal-intestinal valve and phasmid sheath cells. Low levels of expression are also seen in gonadal sheath cells.

Database Links

STRING: 6239.C48B4.4d

UniGene: Cel.6187

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