Recombinant Danio rerio Diencephalon/mesencephalon homeobox protein 1-A (dmbx1a)

Code CSB-YP818294DIL
MSDS
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Source Yeast
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Code CSB-EP818294DIL
MSDS
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Source E.coli
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Code CSB-EP818294DIL-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP818294DIL
MSDS
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Source Baculovirus
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Code CSB-MP818294DIL
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
dmbx1a
Uniprot No.
Alternative Names
dmbx1a; dmbx1; mbx; mbx1; pox1Diencephalon/mesencephalon homeobox protein 1-A; Paired homeobox protein 1
Species
Danio rerio (Zebrafish) (Brachydanio rerio)
Expression Region
1-388
Target Protein Sequence
MQHYGVNGYS LHAMNSLSAM YNLHQQAAQQ AQHAPDYRPS VHALTLAERL AGCTFQDIIL EARYGSQHRK QRRSRTAFTA QQLEALEKTF QKTHYPDVVM RERLAMCTNL PEARVQVWFK NRRAKFRKKQ RSLQKEQLQK QKDVSTDGAL AASDKDEAPS TLNLENQPPS STSSSSSMEA EAAPHALGSE LSVELNVTSA EQSGSESATE DNATDKEEEI KQHREDLKVE KEPAPGNLSP LCKRLSPKPD SPLGSPAISS SSSGVTGGIS QSHSYSSSPL SLFRLQEQFR QHMAATNNLV HYPSFDMATP SSIPYLGMNV NMPAPLGSLP CQSYYQSLSH HAQQVWNSPL LQASGGLPSH NSKTTSIENL RLRAKQHAAS LGLDTLPN
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Required for eye and tectum development. May act as a transcriptional repressor.
Gene References into Functions
  1. Mutual antagonism of the paired-type homeobox genes, vsx2 and dmbx1, regulates retinal progenitor cell cycle exit upstream of ccnd1 expression. PMID: 25872183
  2. Data suggest that both zebrafish dmbx1a and dmbx1b genes are retained in the fish genome due to their requirement during midbrain and retinal neurogenesis, although their function is partially diverged. PMID: 20860823
  3. mbx homeobox gene is required for the development of the eyes and tectum. PMID: 12142024
  4. revealed a pattern of partial spatiotemporal expression divergence between the mbx paralogs that correlates with sequence divergence in noncoding regulatory domains PMID: 16733737
Subcellular Location
Nucleus.
Protein Families
Paired homeobox family
Tissue Specificity
In embryos, expressed in mesencephalon with strongest expression dorsally, diencephalon, and rhombencephalon. During somitogenesis, anterior expression which partly overlaps the future eye field, gradually decreases while midbrain expression intensifies a
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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