Recombinant Dog Secreted frizzled-related protein 2(SFRP2)

Code CSB-YP021139DO
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Source Yeast
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Code CSB-EP021139DO
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Source E.coli
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Code CSB-EP021139DO-B
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP021139DO
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Source Baculovirus
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Code CSB-MP021139DO
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Source Mammalian cell
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Product Details

Purity >85% (SDS-PAGE)
Target Names SFRP2
Uniprot No. Q863H1
Alternative Names SFRP2; Secreted frizzled-related protein 2; sFRP-2
Species Canis lupus familiaris (Dog) (Canis familiaris)
Expression Region 25-294
Target Protein Sequence LFFGQP DFSYKRSNCK PIPANLQLCH GIEYQNMRLP NLLGHETMKE VLEQAGAWIP LVMKQCHPDT KKFLCSLFAP VCLDDLDETI QPCHSLCVQV KDRCAPVMSA FGFPWPDMLE CDRFPQDNDL CIPLASSDHL LPATEEAPKV CEACKNKNED DNDIMETLCK NDFALKIKVK EITYINRDTK IILETKSKTI YKLNGVSERD LKKSVLWLKD SLQCTCEEMN DINAPYLVMG QKLGGELVIT SVKRWQKGQR EFKRISRSIR KLQC
Protein Length Full Length of Mature Protein
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form Lyophilized powder
Buffer before Lyophilization Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting
and FAQs
Protein FAQs
Storage Condition Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet Please contact us to get it.

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Target Data

Function Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis.
Gene References into Functions
  1. secreted Frizzled-related protein 2 induces cellular resistance to apoptosis PMID: 14709558
  2. sFRP2 exerts its anti-apoptotic function in mammary cancer cells through NK-kappaB activation or JNK suppression PMID: 16791480
Subcellular Location Secreted
Protein Families Secreted frizzled-related protein (sFRP) family
Database Links

KEGG: cfa:475471

STRING: 9615.ENSCAFP00000012270

UniGene: Cfa.1200

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