SFRP2

Secreted frizzled-related protein 2 (SFRP2), also known as FRZB2 and SARP2, is a member of the secreted frizzled-related protein family. It acts as a modulator of the Wnt signaling pathway by binding to Wnt proteins, thereby preventing their interaction with frizzled receptors. This interaction is crucial in regulating cell growth, differentiation, and migration during embryonic development and tissue homeostasis.
Dysregulation of SFRP2 has been associated with various diseases, including cancer and fibrosis. In cancer, abnormal SFRP2 expression can lead to uncontrolled cell proliferation. Regarding drug development, there is ongoing research to target the Wnt - SFRP2 axis, aiming to design therapies that can restore normal signaling and potentially treat associated conditions.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

SFRP2 Antibody (CSB-PA021139LA01HU)

Validated Data

Immunofluorescent analysis of Hela cells using CSB-PA021139LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Human Secreted frizzled-related protein 2(SFRP2) ELISA kit (CSB-EL021139HU)

Validated Data

Code: CSB-EL021139HU

Size: 96T,5×96T,10×96T

Sensitivity: 0.039 ng/mL

Detection Range: 0.156 ng/mL-10 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following SFRP2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

SFRP2 Antibodies

SFRP2 Proteins

SFRP2 ELISA Kits

SFRP2 Antibodies

SFRP2 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA021139GA01HU	SFRP2 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA002583	SFRP2 Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA021139LA01HU	SFRP2 Antibody	Human	ELISA, IF
CSB-PA021139LB01HU	SFRP2 Antibody, HRP conjugated	Human	ELISA
CSB-PA021139LC01HU	SFRP2 Antibody, FITC conjugated	Human
CSB-PA021139LD01HU	SFRP2 Antibody, Biotin conjugated	Human	ELISA

SFRP2 Proteins

SFRP2 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP021139MO CSB-EP021139MO CSB-BP021139MO CSB-MP021139MO CSB-EP021139MO-B	Recombinant Mouse Secreted frizzled-related protein 2 (Sfrp2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SFRP2 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

Code	Product Name	Source
CSB-YP021139DO CSB-EP021139DO CSB-BP021139DO CSB-MP021139DO CSB-EP021139DO-B	Recombinant Dog Secreted frizzled-related protein 2 (SFRP2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SFRP2 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP021139HU CSB-EP021139HU CSB-BP021139HU CSB-MP021139HU CSB-EP021139HU-B	Recombinant Human Secreted frizzled-related protein 2 (SFRP2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP021139HU1	Recombinant Human Secreted frizzled-related protein 2 (SFRP2), partial	E.coli

SFRP2 Proteins for Gallus gallus (Chicken)

Code	Product Name	Source
CSB-YP021139CH CSB-EP021139CH CSB-BP021139CH CSB-MP021139CH CSB-EP021139CH-B	Recombinant Chicken Secreted frizzled-related protein 2 (SFRP2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SFRP2 ELISA Kit

SFRP2 ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-EL021139HU	Human Secreted frizzled-related protein 2(SFRP2) ELISA kit	serum, plasma, cell culture supernates, tissue homogenates, cell lysates	0.039 ng/mL

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SFRP2

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