Recombinant Drosophila melanogaster Probable insulin-like peptide 6 (Ilp6)

Code CSB-YP893843DLU
MSDS
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Source Yeast
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Code CSB-EP893843DLU
MSDS
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Source E.coli
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Code CSB-EP893843DLU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP893843DLU
MSDS
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Source Baculovirus
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Code CSB-MP893843DLU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Ilp6
Uniprot No.
Alternative Names
Ilp6; CG14049; Probable insulin-like peptide 6; dILP6; Insulin-related peptide 6) [Cleaved into: Probable insulin-like peptide 6 A chain; Probable insulin-like peptide 6 B chain]
Species
Drosophila melanogaster (Fruit fly)
Expression Region
34-107
Target Protein Sequence
SPLAPTE YEQRRMMCST GLSDVIQKIC VSGTVALGDV FPNSFGKRRK RDLQNVTDLC CKSGGCTYRE LLQYCKG
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Gene References into Functions
  1. it was demonstrated for the first time that insulin-like DILP6 protein in drosophila influences the level of octopamine (regulating the activity of the enzyme degrading octopamine). PMID: 29368833
  2. suggest a feedback system in the interaction between juvenile hormone and DILP6 in which DILP6 negatively regulates the JH titre via an increase in the hormone degradation and a decrease in its synthesis PMID: 27823956
  3. Fat body-derived Drosophila insulin-like peptide 6 induces lipid uptake in oenocytes, promoting lipid turnover during fasting and increasing starvation tolerance. PMID: 25472843
  4. Drosophila insulin-like peptide-6 (dilp6) expression from fat body extends lifespan and represses secretion of Drosophila insulin-like peptide-2 from the brain. PMID: 22935001
  5. Study shows that during metamorphosis, when feeding stops, a specific DILP (Dilp6) is produced by the fat body and relays the growth signal; expression of DILP6 during pupal development is controlled by the steroid hormone ecdysone. PMID: 20059956
  6. Shows that Drosophila insulin-like peptide 6 (DILP6), which is structurally similar to vertebrate insulin-like growth factor (IGF), is predominantly expressed in the fat body, a functional equivalent of the vertebrate liver and adipocytes. PMID: 20059957

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Subcellular Location
Secreted.
Protein Families
Insulin family
Tissue Specificity
Expressed at a low level in the larval gut.
Database Links
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