Recombinant Drosophila melanogaster Zinc finger protein squeeze (sqz), partial

Code CSB-YP894677DLU
MSDS
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Source Yeast
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Code CSB-EP894677DLU
MSDS
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Source E.coli
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Code CSB-EP894677DLU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP894677DLU
MSDS
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Source Baculovirus
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Code CSB-MP894677DLU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
sqz
Uniprot No.
Alternative Names
sqz; CG5557; Zinc finger protein squeeze
Species
Drosophila melanogaster (Fruit fly)
Protein Length
Partial
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
Transcription factor involved in neuronal fate specification. First required in embryonic CNS development to define the number of cells that express apterous (ap) in the ap thoracic cluster of interneurons. Later on, it plays a central role in the combinatorial code of transcription factors that specifies the fate of the Tv neuron in the ap cluster by participating in the transcription regulation of FMRFa in Tv cells. Also required for projection neuron dendritic targeting.
Gene References into Functions
  1. Sqz appears to be a regulatory factor for neuropeptidergic identity common to all leucokinergic cells, whose function in different cell types is regulated by cell-specific factors. PMID: 17442544
Subcellular Location
Nucleus.
Protein Families
Krueppel C2H2-type zinc-finger protein family
Tissue Specificity
Largely restricted to subsets of cells in the CNS throughout embryonic and first instar larval (L1) development. Expressed in a population of lateral interneurons, primarily projecting axons in the anterior and posterior commissures. Overlaps with ap with
Database Links

KEGG: dme:Dmel_CG5557

STRING: 7227.FBpp0083147

UniGene: Dm.2401

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