Recombinant Helix-loop-helix protein 11 (hlh-11)

Code CSB-YP330359CXY
MSDS
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Source Yeast
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Code CSB-EP330359CXY
MSDS
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Source E.coli
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Code CSB-EP330359CXY-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP330359CXY
MSDS
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Source Baculovirus
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Code CSB-MP330359CXY
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
hlh-11
Uniprot No.
Alternative Names
hlh-11; F58A4.7; Helix-loop-helix protein 11
Species
Caenorhabditis elegans
Expression Region
1-431
Target Protein Sequence
MVRSDSAEED QIIIDDGFDL TEEDEEMMSS GTGALPVTIA DWNSVTNARM APPSIMSAAS AFDLTASGMQ NSLRSVLPTS TIGHAPMLAN RSLSQPAPLS PTSLDPDRRS RMRRQIANCN ERRRMQSINA GFLALRALLP RKEGEKLSKA AILQQTADMV HQLLGHKGED IPDGGEPKKL KLEEDHHDAD HQAQIAHLQT ILETERAARK ALESQVIQLR ELLQMTTTSS QASSPVTPRS NGSGGFTLPS SYASSALPTP LRESPERKPS FQDTTSTPLS LLTLNGSPTS SESLASQRIF HPPPTLPSLE TTVIRPTPLP PISVEISSPS LSTPSPLTAA PIIFSTAVPT QSSILFQTAA AAVTSAMSTG NSTPVALPHH LQGHNSAFVS TQPSLTLSQS MQTIVEAIRH LEGSHFIPTS PPPTSQTSLV R
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Transcriptional regulator. Component of a feedback loop involving atfs-1, atgl-1 and hlh-11. Binds to the promoter of the atgl-1 lipase to negatively regulate the expression of atgl-1, and thereby promoting fat oxidation in response to mitochondrial stress and mitochondrial respiration in the intestine. In addition, functions with atfs-1 to maintain lifespan. May have a role in fertility and in positively regulating body size.
Gene References into Functions
  1. hlh-11 may function to regulate serotonin-mediated egg laying at the downstream of tax-6. PMID: 19855932
Subcellular Location
Nucleus.
Tissue Specificity
Expressed in the pharynx, nerve cords, the H-shaped excretory cell, vulva muscles, and the anal depressor (at protein level). Expressed in the intestine (at protein level). In males, it is also expressed in the spicules and hyp7 cells of the hypodermis (a
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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