Recombinant Homeobox protein mab-5 (mab-5)

Code CSB-YP319860CXY
MSDS
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Source Yeast
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Code CSB-EP319860CXY
MSDS
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Source E.coli
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Code CSB-EP319860CXY-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP319860CXY
MSDS
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Source Baculovirus
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Code CSB-MP319860CXY
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
mab-5
Uniprot No.
Alternative Names
mab-5; C08C3.3Homeobox protein mab-5; Protein male abnormal 5
Species
Caenorhabditis elegans
Expression Region
1-200
Target Protein Sequence
MSMYPGWTGD DSYWAGAGTT ASSQSASSGT SASASSSAAA AAAANNLKTY ELYNHTYMNN MKHMLAAGWM DNSSNPFAYN PLQATSANFG ETRTSMPAIS QPVFPWMKMG GAKGGESKRT RQTYSRSQTL ELEKEFHYHK YLTRKRRQEI SETLHLTERQ VKIWFQNRRM KHKKEAKGEG GSNESDEESN QDEQNEQHSS
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Transcription factor that binds to the promoter region of the transcription factor lin-39 to repress its expression in Q neuroblasts and thereby direct left Q neuroblast (QL) daughter cell migration. During postembryonic development, required for posterior-specific pattern formation. Within the posterior body region, controls epidermal, neuronal, and mesodermal cell differentiation.
Gene References into Functions
  1. EGL-20 mediates an acute inhibition of anterior migration independently of BAR-1 and MAB-5, and a later, possible transcriptional response mediated by BAR-1 and MAB-5. PMID: 26863303
  2. Genes regulated by MAB-5 were enriched for those encoding secreted and transmembrane molecules that affect extracellular matrix PMID: 23642123
  3. Data show wild-type mab-5 function is necessary for normal P(9-11).p fate. PMID: 20478294
  4. role of MAB-5 during ray formation; results suggest functional specificity to be conferred by the N-terminal arm and helix I, but not helix II of the homeodomain PMID: 12538523
  5. mab-5 expression was studied in neuroblast lineage in this nematode. PMID: 12930745
  6. In the P11 lineage, a complex between MAB-5 and the Pbx homolog CEH-20 directly regulates transcription of the BH3 domain gene egl-1 to initiate programmed cell death. PMID: 16421192

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Subcellular Location
Nucleus.
Protein Families
Antp homeobox family
Tissue Specificity
Expressed asymmetrically in the QL neuroblast.
Database Links

KEGG: cel:CELE_C08C3.3

STRING: 6239.C08C3.3

UniGene: Cel.18387

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