Recombinant Human Aldo-keto reductase family 1 member B10(AKR1B10)

Code CSB-EP001540HU
Product Type Recombinant Protein
Size US$1726
Uniprot No. O60218
Relevance Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.
Image
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Storage Buffer Tris-based buffer,50% glycerol
Alias ARL-1 Aldose reductase-like Aldose reductase-related protein
Species Homo sapiens (Human)
Purity Greater than 90% as determined by SDS-PAGE.
Sequence MATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACNVLQSSHLEDYPFNAEY
Research Area Signal Transduction
Source E.coli
Gene Names AKR1B10
Protein Names Recommended name: Aldo-keto reductase family 1 member B10 EC= 1.1.1.- Alternative name(s): ARL-1 Aldose reductase-like Aldose reductase-related protein Short name= ARP Short name= hARP Small intestine reductase
Expression Region 1-316aa
Tag Info N-terminal GST-tagged
Mol. Weight 63.0kDa
Protein Description Full Length
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.
Subcellular Location Lysosome, Secreted
Protein Families Aldo/keto reductase family
Tissue Specificity Found in many tissues. Highly expressed in small intestine, colon and adrenal gland.
Database Links

HGNC: 382

OMIM: 604707

KEGG: hsa:57016

STRING: 9606.ENSP00000352584

UniGene: Hs.116724

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